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. 2019 May 24;9:7819. doi: 10.1038/s41598-019-44305-0

Table 3.

Correlation and linear regression slopes between protein and transcript level changes for KEGG pathways for AFB1-, OTA- and ZEN-treated samples.

KEGG pathways AFB1 OTA ZEN Datasize No.gene
rho slope rho slope rho slope
Carbohydrate metabolism 0.332 0.104 0.51 0.155 69
Energy metabolism 0.44 0.147 0.672 0.293 37
Lipid metabolism 0.486 0.171 0.45 0.152 0.359 0.114 77
Nucleotide metabolism 0.391 0.119 0.66 0.174 51
Amino acid metabolism 0.407 0.13 0.63 0.181 0.478 0.144 60
Glycan biosynthesis and metabolism 0.395 0.122 0.41 0.12 0.495 0.178 57
Metabolism of cofactors and vitamins 0.52 0.152 35
Transcription 0.51 0.149 48
Translation 0.48 0.131 0.339 0.149 100
Folding, sorting and degradation 0.66 0.209 0.526 0.222 111
Replication and repair 0.474 0.176 0.73 0.29 0.464 0.222 25
Membrane transport 0.926 0.221 0.9 0.468 11
Signal transduction 0.325 0.141 0.7 0.259 0.412 0.185 186
Signaling molecules and interaction 0.57 0.203 0.462 0.177 137
Transport and catabolism 0.388 0.134 0.65 0.241 126
Cell growth and death 0.497 0.221 0.81 0.326 0.602 0.238 65
Cellular community - eukaryotes 0.42 0.12 0.49 0.169 108
Cell motility 0.66 0.307 42
Immune system 0.412 0.144 0.76 0.272 0.515 0.271 60
Endocrine system 0.7 0.211 0.276 0.109 103
Circulatory system 0.572 0.226 0.57 0.148 44

We only present pathways with data sizes (number of genes) larger than 10, correlation values above 0.3 and p value less than 0.01. Slopes greater than 0.2 are defined as high protein/mRNA changes and formatted with bold font.