Table 3.
Correlation and linear regression slopes between protein and transcript level changes for KEGG pathways for AFB1-, OTA- and ZEN-treated samples.
| KEGG pathways | AFB1 | OTA | ZEN | Datasize No.gene | |||
|---|---|---|---|---|---|---|---|
| rho | slope | rho | slope | rho | slope | ||
| Carbohydrate metabolism | 0.332 | 0.104 | 0.51 | 0.155 | 69 | ||
| Energy metabolism | 0.44 | 0.147 | 0.672 | 0.293 | 37 | ||
| Lipid metabolism | 0.486 | 0.171 | 0.45 | 0.152 | 0.359 | 0.114 | 77 |
| Nucleotide metabolism | 0.391 | 0.119 | 0.66 | 0.174 | 51 | ||
| Amino acid metabolism | 0.407 | 0.13 | 0.63 | 0.181 | 0.478 | 0.144 | 60 |
| Glycan biosynthesis and metabolism | 0.395 | 0.122 | 0.41 | 0.12 | 0.495 | 0.178 | 57 |
| Metabolism of cofactors and vitamins | 0.52 | 0.152 | 35 | ||||
| Transcription | 0.51 | 0.149 | 48 | ||||
| Translation | 0.48 | 0.131 | 0.339 | 0.149 | 100 | ||
| Folding, sorting and degradation | 0.66 | 0.209 | 0.526 | 0.222 | 111 | ||
| Replication and repair | 0.474 | 0.176 | 0.73 | 0.29 | 0.464 | 0.222 | 25 |
| Membrane transport | 0.926 | 0.221 | 0.9 | 0.468 | 11 | ||
| Signal transduction | 0.325 | 0.141 | 0.7 | 0.259 | 0.412 | 0.185 | 186 |
| Signaling molecules and interaction | 0.57 | 0.203 | 0.462 | 0.177 | 137 | ||
| Transport and catabolism | 0.388 | 0.134 | 0.65 | 0.241 | 126 | ||
| Cell growth and death | 0.497 | 0.221 | 0.81 | 0.326 | 0.602 | 0.238 | 65 |
| Cellular community - eukaryotes | 0.42 | 0.12 | 0.49 | 0.169 | 108 | ||
| Cell motility | 0.66 | 0.307 | 42 | ||||
| Immune system | 0.412 | 0.144 | 0.76 | 0.272 | 0.515 | 0.271 | 60 |
| Endocrine system | 0.7 | 0.211 | 0.276 | 0.109 | 103 | ||
| Circulatory system | 0.572 | 0.226 | 0.57 | 0.148 | 44 | ||
We only present pathways with data sizes (number of genes) larger than 10, correlation values above 0.3 and p value less than 0.01. Slopes greater than 0.2 are defined as high protein/mRNA changes and formatted with bold font.