Table 1.
Characteristics of patients at ICU admission
| Characteristic | pO2 ≤ 120 mmHg N = 214 | pO2 > 120 mmHg N = 119 | Significance level (p value) |
|---|---|---|---|
| Age in years | 71 (60–78) | 71 (57–77) | 0.49 |
| Male sex | 107 (50.0) | 55 (46.2) | 0.51 |
| Body mass index | 27 (25–30) | 26 (24–28) | 0.02 |
| History of smoking | 66 (30.8) | 31 (26.1) | 0.36 |
| Baseline Rankin | 0.95 | ||
| 0 | 151 (70.9) | 86 (72.3) | 0.79 |
| 1 | 44 (20.7) | 19 (16.0) | 0.30 |
| ≥ 2 | 18 (8.5) | 14 (11.8) | 0.33 |
| Hypertension | 150 (70.1) | 75 (63.0) | 0.19 |
| Dyslipidemia | 96 (44.9) | 48 (40.3) | 0.42 |
| Diabetes mellitus | 61 (28.5) | 34 (28.6) | 0.99 |
| History of COPDa | 19 (8.9) | 7 (5.9) | 0.33 |
| History of CRFb | 12 (5.6) | 7 (5.9) | 0.92 |
| Atrial fibrillation/flutter | 88 (41.1) | 45 (37.8) | 0.55 |
| Previous stroke | 26 (12.1) | 12 (10.1) | 0.57 |
| Previous antiaggregating therapy | 64 (29.9) | 39 (32.8) | 0.59 |
| Previous anticoagulation therapy | 35 (16.4) | 18 (15.1) | 0.77 |
| Preprocedure GCS | 14 (13–15) | 14 (12–15) | 0.44 |
| Preprocedure NIHSS | 18 (12–21) | 19 (14–22) | 0.09 |
| APACHE | 15 (12–19) | 16 (12–22) | 0.23 |
| Findings in CT scan | 0.11 | ||
| Without ischemia | 80 (38.1) | 53 (44.5) | 0.25 |
| Acute ischemic areasc | 103 (49.0) | 59 (49.6) | 0.93 |
| Areas of ancient stroke | 27 (12.9) | 7 (5.9) | 0.05 |
| Mismatch | 70 (50–80) | 70 (50–80) | 0.43 |
| Etiology of stroke | 0.01 | ||
| Cardioembolic | 96 (44.9) | 34 (28.6) | < 0.01 |
| Atherothrombotic | 69 (32.2) | 48 (40.3) | 0.14 |
| Idiopathic | 49 (22.9) | 37 (31.1) | 0.10 |
| Wake-up stroke | 25 (11.7) | 12 (10.1) | 0.66 |
| Time (min.) onset of symptoms—IAMT | 270 (210–367) | 300 (220–398) | 0.24 |
| Type of intervention | 0.85 | ||
| Thrombectomy | 180 (84.1) | 101 (84.9) | |
| Thrombectomy + stent | 34 (15.9) | 18 (15.1) | |
| Reperfusion degreee | 0.18 | ||
| Successful reperfusion | 201 (93.9) | 107 (89.9) | |
| Non-successful reperfusion | 13 (6.1) | 12 (10.1) | |
| OTI at admissione | 97 (45.3) | 79 (66.4) | < 0.01 |
| MAPf | 87 (73–98) | 90 (77–103) | 0.22 |
This table value of quantitative variables expressed as median and interquartile range. Values of qualitative variables expressed as n (%)
aChronic obstructive pulmonary disease
bCreatinine clearance < 60 ml/min/1.73 m2
cIncluded signs of acute ischemia and indirect signs of ischemia: hyperdense middle cerebral artery sign, hemispheric sulcus and/or insular cortex effacement, contrast attenuation, ventricular compression
dSuccessful reperfusion included TICI 2b and TICI 3. Non-successful reperfusion includes TICI ≤ 2a
ePatients intubated at ICU admission after IAMT
fMean arterial pressure at ICU admission after IAMT