Table 2.
Safety attributes | Scoring | ||||
---|---|---|---|---|---|
Cladribine tablets | Fingolimod | Natalizumab | Ocrelizumab | Alemtuzumab | |
Availability of long-term safety data | 7.5 | 6.5 | 8.1 | 7.2 | 7.2 |
Low risk of malignancy | 7.3 | 6.6 | 6.4 | 6.8 | 5.8 |
Good benefit vs. risk profile | 7.4 | 5.7 | 7.3 | 6.9 | 6.2 |
Good short- and long-term safety profile | 7.7 | 5.8 | 6.7 | 6.8 | 5.8 |
Low risk of PML | 7.9 | 5.9 | 5.4 | 7.2 | 6.8 |
Relatively well tolerated | 7.5 | 6.8 | 7.0 | 7.8 | 6.2 |
DMD disease-modifying drug, PML progressive multifocal leukoencephalopathy