Table 2.
Demographic and clinical characteristics of 106 C. perfringens-positive patients.
| Patient characteristics | AAD group (n=68) | Non-AAD group (n=38) |
Total (%) (n=106) |
P value* |
|---|---|---|---|---|
| Age (years) | ||||
| 1–10 | 5 (7.4) | 8 (21) | 13 (12.3) | 0.001 |
| 11–20 | 2 (2.9) | 2 (5.2) | 4 (3.8) | |
| 21-30 | 18 (26.5) | 12 (31.7) | 30 (28.3) | |
| 31-40 | 9 (13.2) | 9 (23.7) | 18 (16.9) | |
| 41-50 | 9 (13.2) | 4 (10.5) | 13 (12.2) | |
| >50 | 25 (36.8) | 3 (7.9) | 28 (26.5) | |
| Gender | ||||
| Female | 36 (53) | 20 (52.6) | 56 (52.8) | 1 |
| Male | 32 (47) | 18 (47.4) | 50 (47.2) | |
| Duration of diarrhea | ||||
| 2-3 days | 51 (75) | 25 (65.8) | 76 (71.7) | 0.37 |
| >3 days | 17 (25) | 13 (32.2) | 30 (28.3) | |
| Defecation (times/day) | ||||
| 3–5 | 45 (66.2) | 20 (53) | 65 (61.4) | 0.21 |
| 5–8 | 13 (19.1) | 14 (36.5) | 27 (25.4) | |
| 8–10 | 9 (13.2) | 4 (10.5) | 13 (12.3) | |
| >10 | 1 (1.5) | 0 | 1 (0.9) | |
| Underlying diseases | ||||
| Cancer | 13 (19.1) | 4 (10.5) | 17 (16) | 0.59 |
| Renal failure | 2 (2.9) | 0 | 2 (1.9) | |
| Dementia | 2 (2.9) | 0 | 2 (1.9) | |
| Immunodeficiency disorders | 2 (2.9) | 1 (2.7) | 3 (2.8) | |
| Inflammatory bowel disease (IBD) | 37 (54.5) | 23 (60.5) | 60 (56.7) | |
| Inflammatory bowel syndrome (IBS) | 1 (1.5) | 1 (2.6) | 2 (1.9) | |
| Hospital wards | ||||
| Internal | 9 (13.2) | 3 (7.9) | 12 (11.3) | 0.21 |
| Gastroenterology | 31 (45.6) | 16 (42.1) | 47 (44.3) | |
| Infectious | 2 (2.9) | 2 (5.2) | 4 (3.8) | |
| Oncology | 10 (14.7) | 1 (2.7) | 11 (10.4) | |
| Intensive care unit (ICU) | 1 (1.5) | 1 (2.7) | 2 (1.9) | |
| Coronary care unit (CCU) | 1 (1.5) | 0 | 1 (0.9) | |
| Bone marrow transplantation (BMT) | 2 (2.9) | 1 (2.7) | 3 (2.8) | |
| Nephrology | 1 (1.5) | 1 (2.7) | 2 (1.9) | |
| Orthopedic | 1 (1.5) | 0 | 1 (0.9) | |
| Out-patient | 10 (14.7) | 13 (34.2) | 23 (21.8) | |
AAD, antibiotic-associated diarrhea.
*Statistical analysis was performed by Chi-square and Fisher’s exact tests. The P value in bold indicates a significant association between AAD and patients’ age over 50 years.