Table 3. Adverse events related to the treatment including grade 3 and grade 4 adverse events.

Adverse events	Grade 1, n (%)	Grade 2, n (%)	Grade 3, n (%)	Grade 4, n (%)
Heart failure			1 (2.78)
Colon fistula/perforation			2 (5.56)
Small bowel obstruction			1 (2.78)
Fatigue	15 (41.67)	6 (16.67)	2 (5.56)
Bacteremia			2 (5.56)
LFT abnormalities			3 (8.34)
Anorexia	12 (33.34)		1 (2.78)
UTI			1 (2.78)
Urinary retention			1 (2.78)
Generalized muscle weakness			2 (5.56)
Neuropathy			2 (5.56)
Dyspnea	8 (22.23)		1 (2.78)
Respiratory failure				1 (2.77)
Hypertension			3 (8.34)
Thromboembolic event			1 (2.78)
Abdominal pain	6 (16.67)
Constipation	11 (30.56)
Diarrhea	14 (38.89)	3 (8.34)
Nausea	14 (38.89)
Vomiting	10 (27.78)	2 (5.56)
Headache	9 (25.00)
Cough	10 (27.78)
Dry skin	8 (22.23)
Hand-Foot syndrome	6 (16.67)	5 (13.89)

LFT, liver function tests; UTI, urinary tract infection.