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Total Number of Unique, Small Molecule Drugs Listed in the Orange Book, 2005–2015.
| Year | Total no of Drugs Listed (at the New Drug Application Level) |
|---|---|
| 2005 | 2402 |
| 2006 | 2354 |
| 2007 | 2354 |
| 2008 | 2353 |
| 2009 | 2362 |
| 2010 | 2397 |
| 2011 | 2425 |
| 2012 | 2436 |
| 2013 | 2470 |
| 2014 | 2533 |
| 2015 | 2547 |
| 2005–2015 (number of unique drugs throughout the period) | 3372 |
