Figure 1.
Diosmetin (Dio) selectively inhibits non‐small‐cell lung cancer (NSCLC) cell viability. (a) The structure of diosmetin. (b) Diosmetin treatment induces cell death in NSCLC cells but does not induce cell death in normal cells. The effect of diosmetinon the viability of the NSCLC cells A549, H1299, H441, H460, SPC, Calu‐3, and H1650 and the normal cells HLF‐1 and BEAS‐2B by MTT assay at the indicated concentration. The IC50 (mean ± SD; n = 5) of diosmetin against tumour cell lines. (c) Time‐dependent action of diosmetin on the viability of the A549 and H1299 cells as assessed by MTT. *P < 0.05, significantly different from control group