TABLE 1.
Type -in mentions of new and uncommon drugs, 2005–2017
| 2C-x | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| 2C-B (Bromo mescaline, Nexus) | 9 | 11 | 19 | 13 | 20 | 34 | 50 | 35 | 33 | 48 | 40 | 33 | 34 | 379 |
| 2C-I (2,5-Dimethoxy-4-iodophenethylamine) | 13 | 17 | 10 | 18 | 30 | 36 | 42 | 41 | 51 | 41 | 40 | 37 | 34 | 410 |
| 2C-E (2–5-Dimethoxy-4-ethyl-phenethylamine) | 4 | 5 | 6 | 12 | 10 | 28 | 29 | 31 | 49 | 22 | 24 | 14 | 19 | 253 |
| 2C-T-2 | 2 | 2 | 4 | 1 | 1 | 4 | 3 | 3 | 1 | 2 | 1 | 1 | 2 | 27 |
| 2C-T-7 (T7, Blue Mystic) | 2 | 4 | 2 | 1 | 2 | 3 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 21 |
| 2C-D (2,5-Dimethoxy-4-methylphenethylamine) | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 3 |
| 2C-T (2,5-Dimethoxy-4-methylthiophenethylamine) | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 5 |
| 2C-T-21 (2,5-dimethoxy-4-(2-fluoroethylthio)phenethylamine) | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4 |
| 2C-C (2–5-Dimethoxy-4-chlorophenethylamine) | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5 |
| 2C-BCB (TCB-2) | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 4 |
| 2C-P (4-propyl-2,5-dimethoxyphenethylamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 9 | 2 | 7 | 6 | 4 | 29 |
| 2C-F (2,5-dimethoxy-4-fluorobenzaldehyde) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 2C-C (4-chloro-2,5-dimethoxyphenethylamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 0 | 1 | 5 |
| 2C-B-Fly (2C-Bromo-Fly) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
| 2C-x total | 30 | 40 | 42 | 46 | 66 | 107 | 125 | 115 | 147 | 121 | 116 | 94 | 96 | 1145 |
| DOx | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| DOM (STP) | 4 | 1 | 5 | 1 | 1 | 3 | 1 | 2 | 3 | 6 | 1 | 4 | 1 | 33 |
| DOI (2,5-Dimethoxy-4-iodoamphetamine) | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 2 | 0 | 8 |
| DOC (2,5-dimethoxy-4-chloroamphetamine) | 0 | 0 | 0 | 4 | 0 | 5 | 2 | 2 | 4 | 1 | 3 | 2 | 2 | 25 |
| DOB (2,5-dimethoxy-4-bromoamphetamine) | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 2 | 3 | 3 | 2 | 0 | 1 | 20 |
| DOx Total | 4 | 1 | 6 | 5 | 7 | 12 | 5 | 7 | 10 | 11 | 6 | 8 | 4 | 86 |
| NBOMe | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| 251-NBOMe (2C-l-NBOMe, BOM-CI, Cimbi-5) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 23 | 22 | 26 | 20 | 15 | 114 |
| 25C-NBOMe (2C-C-NBOMe, NBOMe-2C-C) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | 3 | 8 | 3 | 3 | 24 |
| 25B-NBOMe (NBOMe-2C-B) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2 | 2 | 3 | 10 |
| NBOMe, otherwise unspecified | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 2 | 9 |
| 25D-NBOMe | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
| NBOMe Total | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 30 | 27 | 39 | 29 | 24 | 158 |
| Other Phenethylamines | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| MDA (Methylenedioxyamphetamine) | 3 | 10 | 11 | 7 | 14 | 8 | 10 | 19 | 10 | 11 | 2 | 5 | 7 | 117 |
| PMA (Paramethoxyamphetamine) | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| DMA (2, 5-Dimethoxyamphetamine) | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 6 |
| TMA (Trimethoxyamphetamine) | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
| PMMA (Paramethoxymethamphetamine) | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 3C-Bromo-Dragonfly (DOB-Dragonfly) | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 1 | 2 | 0 | 8 |
| MDE (MDEA, 3,4-Methylenedioxy-N-Ethylamphetamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 5 |
| 4-FMA (4-Fluoromethamphetamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 2 |
| 6-APB, Benzo Fury | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 3 |
| 5-MAPB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 2 |
| 6-MAPB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
| 4-FA (4-Fluoroamphetamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 |
| 5-APB | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
| 3,4-Ethylenedioxy-N-methylamphetamine (EDMA, MDMC) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
| Other Phenethylamine Total | 5 | 12 | 12 | 7 | 17 | 8 | 11 | 19 | 16 | 16 | 4 | 10 | 16 | 153 |
| Phenethylamine Total | 39 | 53 | 60 | 58 | 90 | 127 | 141 | 150 | 203 | 175 | 165 | 141 | 140 | 1542 |
| Synthetic Cathinones | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| bk-MDMA (Methylone) | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 4 | 1 | 3 | 2 | 2 | 16 |
| MCAT (Mephedrone) | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 5 | 2 | 2 | 1 | 0 | 2 | 17 |
| Methedrone | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 |
| MDPV (Methylenedioxypyrovalerone) | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 2 | 1 | 2 | 1 | 0 | 11 |
| Bath salts, otherwise unspecified | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 11 | 10 | 6 | 11 | 1 | 4 | 44 |
| Cloud 10 Ultra | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| alpha-PVP (alpha-Pyrrolidinopentiophenone) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 2 |
| Beta-keto 2C-B (Bk-2C-B) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
| Synthetic Cathinones Total | 0 | 0 | 0 | 0 | 1 | 4 | 8 | 20 | 19 | 10 | 18 | 6 | 8 | 94 |
| Tryptamines | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| AMT (Alpha-methyltryptamine, IT-290, 3-IT) | 15 | 7 | 5 | 8 | 6 | 1 | 5 | 2 | 0 | 7 | 1 | 1 | 0 | 58 |
| Foxy | 3 | 3 | 3 | 1 | 2 | 3 | 2 | 2 | 2 | 0 | 0 | 1 | 0 | 22 |
| 5-MeO-DiPT (Foxy methoxy) | 3 | 2 | 1 | 4 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 1 | 0 | 17 |
| 5-MeO-AMT | 3 | 1 | 4 | 1 | 4 | 2 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 20 |
| DiPT (Di-isopropyl-tryptamine) | 2 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6 |
| 5-MeO-DMT | 1 | 5 | 4 | 2 | 4 | 2 | 3 | 1 | 3 | 2 | 1 | 1 | 3 | 32 |
| DPT (Dipropyltryptamine) | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 6 |
| 5-MeO-T (5-methoxytryptamine) | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| 4-AcO-DMT (4-HO-DMT, 4-acetoxy-N,N-dimethyltryptamine) | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 3 | 2 | 9 | 5 | 3 | 27 |
| 5-MeO, otherwise unspecified | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 2 | 8 |
| 4-HO-DiP (4-HO-DiPT, 4-Hydroxy-N,N-diisopropyltryptamine) | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 |
| 4-Hydroxy-MIPT (4-HO-MiPT) | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 |
| 4-HO-MET (N-Ethyl-4-hydroxy-N-methyltryptamine) | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 1 | 4 |
| 5-MeO-MiPT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 4 |
| 4-MeO-DMT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
| 4-HO-DET (CZ-74, Ethocin) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
| 4-AcO-MET (4-Acetoxy-MET, Metacetin) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
| Synthetic mushrooms (unspecified) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
| Tryptamine Total | 28 | 21 | 19 | 17 | 20 | 15 | 14 | 8 | 15 | 15 | 15 | 14 | 13 | 214 |
| Synthetic Cannabinoids | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| Synthetic cannabinoids (e.g., K2, Spice, JWH-018) | 0 | 0 | 0 | 0 | 0 | 9 | 28 | 33 | 49 | 29 | 33 | 25 | 26 | 232 |
| CP 55,940 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
| Synthetic cannabis, otherwise unspecified | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 1 | 1 | 3 | 2 | 12 |
| AM-2201 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2 |
| Synthetic Cannabinoids Total | 0 | 0 | 0 | 0 | 0 | 10 | 28 | 38 | 51 | 30 | 34 | 28 | 28 | 247 |
| Lysergamides | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| LSA | 10 | 12 | 13 | 15 | 13 | 27 | 23 | 14 | 18 | 16 | 12 | 14 | 20 | 207 |
| ALD-52 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 |
| LSZ (Lysergic acid 2,4-dimethylazetidide) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 3 |
| LAH (LSH, Lysergic acid hydroxyethylamide) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
| AL-LAD (6-allyl-6-nor-LSD) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 |
| IP-LSD | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 |
| Synthetic LSD/acid (unspecified) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
| Lysergamides Total | 10 | 12 | 13 | 15 | 13 | 28 | 23 | 15 | 19 | 17 | 15 | 16 | 22 | 218 |
| Dissociatives | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| 3-MeO-2-Oxo-PCE (MXE, Methoxetamine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4 | 2 | 4 | 9 | 23 |
| Cl-400 (Eticyclidine, PCE) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 3-MeO-PCP (3-Methoxyphencyclidine) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
| Dissociative Total | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 4 | 2 | 5 | 9 | 25 |
| Piperazines | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | Total |
| BZP (Benzylpiperazine) | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3 |
| Piperazines Total | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3 |
| Total | 77 | 86 | 93 | 90 | 124 | 185 | 214 | 233 | 311 | 251 | 249 | 210 | 220 | 2343 |
Note. NSDUH staff classified typed-in responses into precoded response options for previously reported drugs and coded new responses for first reported drugs. The drug names listed above represent NSDUH classification–some of which contain full chemical names or street names and others do not. We did not make major edits to response options for transparency.