Table 1.
Characteristics of study participants
| BPD n = 26 |
Preterm n = 23 |
Asthma n = 23 |
Healthy controls n = 24 |
|
|---|---|---|---|---|
| Sex, Male/Female | 11/15 | 10/13 | 10/13 | 12/12 |
| Age, years |
19.6* (18.2;21.2) |
19.1** (18.3;22.4) |
20.2 (18.6;23.3) |
20.5 (18.3;23.8) |
| Weight, kg M/F |
69.6/61.5 (48;109.9)/(44.5;88) |
68/59.2 (55;85.5)/(44;72.4) |
75.7/59 (62;89)/(48;106) |
71.8/ 62 (56.5;117.4)/(44.8;112) |
| Length, cm M/F |
175/166 (155;192)/(155;173) |
182/165 (169;192)/ (152;173) |
174/168 (164;182)/(150;176) |
180/167 (168;194)/(151;190) |
| BMI, m/kg2 M/F |
20/22 (18;30)/(18;32) |
20/ 21 (17;28)/(17;28) |
24/21 (21;29)/(18;34) |
21.5/22 (20;33)/(18;38) |
| FeNO, ppb |
14.9 (9.2;22.2) |
13.1 (11;19.8) |
31.4** (11.6;49.2) |
10.9 (9.7;17.1) |
| Positive Phadiatop | 3 (12) | 8 (35) | 23 (100) | 0 |
| Blood Eosinophils 1 × 102/μL |
0.1 (0.0;0.3) |
0.0 (0.0;0.2) |
0.3*** (0.0;0.7) |
0.0 (0.0;0.5) |
| CRP, mg/L |
0.35 (0;2.1) |
0.32 (0;1.3) |
0.46 (0;7.6) |
0.34 (0;7.7) |
| Alpha-1 antitrypsin g/L |
1.4 (0.8;1.7) |
1.3 (1.0;1.7) |
1.4 (1.1;1.8) |
1.4 (1.1;1.9) |
| Antidepressant medication | 1 (3.8) | 2 (8.7) | 2 (8.7) | 1 (4.1) |
| ADHD/ADD medication | 3 (11.5) | 3 (13) | 0 | 1 (4.1) |
Data are presented as median (range) or numbers (%). Abbreviations: BPD bronchopulmonary dysplasia, M male, F female, BMI body mass index, FeNO fractional exhaled nitric oxide, CRP C-reactive protein, ADHD Attention deficit hyperactivity disorder, ADD Attention deficit disorder
*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 (compared to healthy)