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. 2019 May 24;17:176. doi: 10.1186/s12967-019-1921-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The effect of intervention genotype categories. Gray is used for the graphs of the intervention group and black is used for the graphs of the control group. In risk allele carriers, IRX3 expression was unchanged in the control group and up-regulated in the intervention group (P = 0.017)