Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 24;17:52. doi: 10.1186/s12964-019-0360-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 4 — Co-inhibition by SN (100 nM) and CAP (180 s) in G-361 cellular death induction by different mechanisms. (a) Caspase 8, (b) caspase 9 and (c) caspase 3/7 levels by using spectrophotometrically (d) Immunoblot showing the detection of PARP/cleaved PARP, Bcl-2, caspase cleavage, Bax and the p53 activation status (e) Cleaved PARP estimation in different groups using spectrophotometrically. (f) The m-RNA expression levels of PARP-1, ATM, p53, BAX, and Bcl-2 were estimated using RT-PCR (g) Apoptotic cell death (annexin V/PI staining) was measured using flow cytometry. Error bars indicate the ±SD (n = 3). Student’s t-tests were performed, and the levels of significance are indicated as follows: ^*, p < 0.05; ^δ, p < 0.01; and ^#, p < 0.001