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. Author manuscript; available in PMC: 2020 Feb 27.
Published in final edited form as: Sci Transl Med. 2019 Feb 27;11(481):eaav4319. doi: 10.1126/scitranslmed.aav4319

Fig. 1. NF-κB signaling in clinical tendinopathy.

Fig. 1.

(A) Heat map of NF-κB profiling gene expression array from healthy human hamstrings tendons (control, n = 4) and early-stage diseased tendons (tendinopathy, n = 5). (B) Volcano plot of NF-κB profiling gene expression array. P < 10−6 are scaled for visualization purposes. (C) NF-κB complex protein coding genes NFKB1, REL, and RELB in control and tendinopathy tendon samples. (D) Regulatory NF-κB protein coding genes CHUK, IKBKB, IKBKE, and NFKBIE in control and tendinopathy tendon samples. Data are shown as means ± SD with individual points representing biologically independent samples. Statistically significant differences were calculated using multiple t tests with Holm-Šídák correction, **P < 0.01 and *P < 0.05.