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. Author manuscript; available in PMC: 2020 Feb 27.
Published in final edited form as: Sci Transl Med. 2019 Feb 27;11(481):eaav4319. doi: 10.1126/scitranslmed.aav4319

Fig. 5. Small-molecule inhibition of IKKβ in an in vitro model of inflammation.

Fig. 5.

(A) Volcano plots of NF-κB signaling array in healthy human tendon fibroblasts treated with IL-1β with or without IKKβ inhibitor. (B) Proinflammatory cytokines IL-6 and CCL-2 produced by healthy human tendon fibroblasts treated with IL-1β with or without IKKβ inhibitor. Data are shown as means ± SD. Statistically significant differences were calculated using one-way ANOVA (treatment) with Fisher’s LSD post hoc test. *P < 0.05.