Table 1.

Paget’s-like changes, p62 reactivity and endogenous DNA in bone and tooth samples

Skeleton	Macroscopic/radiographic Paget’s-like changes	Samples (p62 reactivity*)	Samples (endogenous DNA†)
SK101	Yes‡	Petrous (+), Femur (−)	Petrous (32.1%)
SK52	Yes	Petrous (−), Femur (−)	Petrous (47.2%)
SK29	Yes	Tooth (+)	Tooth (4.1%)
SK22	Yes	Tooth (−)	Tooth (26.8%)
SK35	Yes	Tooth (−), Femur (+)	Tooth (1.3%)
SK55	Yes	—	Rib (0.0004%)
SK32	Yes	Petrous (−)	—
SK37	Yes	Petrous (+)	—
SK27	No	Petrous (−)	—
SK28	No	Petrous (−)	—

(+), positive; (−), negative; —, not tested.

^*p62 immunoreactivity in the indicated samples was assessed by Western blotting with mouse-anti-p62 antibodies.

^†Endogenous DNA content for different skeletal samples as indicated.

^‡Indicates clear Paget’s like macroscopic and/or radiographic changes in bone.