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Reversal of fibrosis in the liver is linked to one of several cellular processes involving stellate cells. Stellate cells may revert to an inactive, or quiescent state (by remain primed for reactivation). They may also be eliminated via either apoptosis or autophagy. The ultimate effect of many of these processes is controversial from a cell biological standpoint, since they may actually stimulate activation of stellate cells and therefore stimulate fibrogenesis.
