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(A–I) Expression and phosphorylation of target proteins in chondrocytes. (A) electrophoretic profile; (B) Col10 expression; (C) total NF-κB-p65 expression; (D) Mmp13 expression; (E) phospho-NF-κB-p65 expression; (F) phosphor-IKKα/β expression; (G) PARP expression; (H) phosphor-c-Jun expression; (I) cleaved-PARP expression. (J) deduced process of relative TNF signaling pathway. Values are shown as mean ± SD. ##P < 0.01 vs. normal cells; *P < 0.05 or **P < 0.01 vs. TNF-α treated cells.
