TABLE 2.
SVR Rates (and 95% Cl) by Race/Ethnicity Among Clinically Relevant Subgroups
| All Patients (n = 19,286) |
White (n = 10,180) |
Black (n = 5,615) |
Hispanic (n = 1,013) |
Asian/PI/AI/AN (n = 324) |
Declined/ Missing (n = 2,154) (%, 95% Cl) |
|||
|---|---|---|---|---|---|---|---|---|
| All patients | 89.6 (89.2–90.1) | 89.8 (89.2–90.4) | 89.8 (89.0–90.6) | 86.0 (83.7–88.0) | 90.7 (87.0–93.5) | 90.0 (88.6–91.2) | ||
| Genotype/regimen | ||||||||
| 1 | 91.1 (90.6–91.5) | 91.9 (91.3–92.5) | 90.3 (89.5–91.1) | 88.0 (85.6–90.1) | 92.4 (88.5–95.1) | 90.8 (89.3–92.0) | ||
| SMV + SOF | 84.4 (83.1–85.7) | 86.0 (84.2–87.7) | 82.1 (79.4–84.5) | 81.3 (75.5–86.0) | 90.9 (79.5–96.3) | 84.6 (78.6–89.1) | ||
| SMV+SOF+RIBA | 87.0 (84.0–89.6) | 88.1 (84.0–91.3) | 86.1 (79.8–90.6) | 78.1 (59.6–89.7) | N/A | 86.4 (72.1–93.9) | ||
| LDV/SOF | 92.8 (92.2–93.4) | 94.1 (93.3–94.9) | 92.0 (90.9–93.0) | 89.7 (85.5–92.7) | 91.5 (84.3–95.6) | 91.3 (89.2–93.0) | ||
| LDV/SOF+RIBA | 92.0 (90.9–93.0) | 92.4 (90.8–93.7) | 92.1 (89.8–94.0) | 91.1 (85.7–94.6) | 95.6 (83.1–98.9) | 90.5 (86.9–93.3) | ||
| PrOD | 94.9 (93.0–96.3) | 96.1 (93.1–97.8) | 93.4 (90.1–95.7) | N/A | N/A | 95.4 (88.2–98.3) | ||
| PrOD+RIBA | 92.5 (91.3–93.5) | 92.5 (90.7–93.9) | 92.3 (90.0–94.1) | 93.5 (86.9–96.9) | 90.7 (76.9–96.6) | 92.9 (89.1–95.4) | ||
| 2 | 86.2 (84.5–87.7) | 86.7 (84.8–88.4) | 78.9 (72.0–84.5) | 85.0 (76.8–90.7) | 82.8 (63.3–93.0) | 89.0 (84.4–92.4) | ||
| SOF+RIBA | ||||||||
| 3 | 74.8 (72.2–77.3) | 74.3 (71.3–77.2) | 74.4 (57.8–86.0) | 69.9 (59.0–78.9) | 83.3 (64.3–93.3) | 79.8 (71.5–86.2) | ||
| LDV/SOF+RIBA | 77.9 (73.2–82.0) | 76.8 (71.1–81.6) | N/A | 67.9 (47.5–83.1) | N/A | 84.4 (70.1–92.6) | ||
| SOF+PEG+RIBA | 87.0 (80.0–91.8) | 87.5 (78.6–93.0) | 87.5 (31.9–99.1) | 91.7 (49.9–99.2) | 100 | 78.9 (52.7–92.7) | ||
| SOF+RIBA | 70.6 (66.9–74.1) | 70.7 (66.5–74.6) | 62.5 (40.6–80.2) | 65.1 (49.3–78.2) | 75.0 (45.7–91.4) | 76.4 (63.0–86.0) | ||
| 4 | 89.6 (82.8–93.9) | 91.3 (81.6–96.1) | 90.7 (76.9–96.6) | N/A | N/A | N/A | ||
| LDV/SOF or PrOD ± RIBA | ||||||||
| No cirrhosis | 92.2 (91.7–92.7) | 92.7 (92.1–93.3) | 91.3 (90.4–92.2) | 89.7 (86.8–92.0) | 92.4 (87.9–95.3) | 93.2 (91.7–94.4) | ||
| Cirrhosis | 84.8 (83.9–85.6) | 84.4 (83.2–85.6) | 86.5 (84.8–88.0) | 82.0 (78.4–85.2) | 87.7 (80.2–92.6) | 83.7 (80.8–86.2) | ||
| Decompensated cirrhosis | 79.5 (77.6–81.3) | 80.6 (78.2–82.7) | 78.4 (73.4–82.6) | 72.5 (64.9–79.1) | 85.7 (68.9–94.2) | 79.3 (73.1–84.4) | ||
| HIV | 91.1 (88.9–92.9) | 93.9 (89.2–96.6) | 90.3 (87.1–92.7) | 93.5 (83.6–97.6) | N/A | 87.1 (77.9–92.8) | ||
| Liver transplantation | 93.8 (91.5–95.5) | 95.7 (93.0–97.3) | 89.1 (80.8–94.1) | 86.0 (71.5–93.8) | N/A | 93.5 (83.6–97.6) | ||
| Treatment-naive | 89.6 (89.1–90.1) | 90.0 (89.3–90.7) | 89.3 (88.3–90.2) | 86.9 (84.2–89.1) | 91.7 (87.5–94.5) | 89.9 (88.2–91.3) | ||
| Treatment-experienced | 89.7 (88.7–90.5) | 89.1 (87.8–90.3) | 91.7 (90.1–93.1) | 83.6 (78.8–87.5) | 87.5 (77.4–93.5) | 90.3 (87.6–92.4) | ||
Abbreviation: N/A, not applicable due to fewer than 15 patients in this subgroup.