. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Mass Spectrom Rev. 2018 Nov 25;38(3):265–290. doi: 10.1002/mas.21583

TABLE 2.

Diagnostic performance of current markers for early HCC detection.

Symbol	Name	AUC	Early Detection		Reference
Symbol	Name	AUC	Sensitivity(%)	Specificity(%)	Reference
AFP	Alpha-fetoprotein	0.8	53	90	(Marrero et al., 2009)
DCP	Des-gamma carboxy prothrombin	0.72	61	70	(Marrero et al., 2009)
AFP-L3	Alpha-fetoprotein (binds to LCA)	0.66	28	97	(Marrero et al., 2009)
GP73	Golgi protein 73	0.77	62	88	(Marrero et al., 2005)
AFP + DCP		0.83	78	62	(Marrero et al., 2009)