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. 2019 Mar 14;39(5):619–636. doi: 10.1007/s10571-019-00667-7

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 8 — X-ray spectroscopy of Pt L_III edge in samples prepared by mixing cisplatin alone or with WR1065 with complex biological molecules DNA and BSA or by treating whole NT2-N cells with cisplatin with or without WR1065. a Comparison of Pt edge in cisplatin alone with Pt edge in a mixture of cisplatin and WR1065. Energy shift ΔE = 0.35 ± 0.04 eV suggests a change in the chemical environment of Pt when cisplatin is mixed with WR1065. b Comparison of Pt edge in cisplatin and WR1065 treated cells vs. mixtures of cisplatin and WR1065 and salmon sperm DNA (ΔE = 0.70 eV) or BSA (ΔE = 0.40 eV). c Comparison of the Pt edge in cisplatin treated cells vs. mixtures of cisplatin and salmon sperm DNA (ΔE = 0.60 eV) or BSA (ΔE = 0.45 eV)