Table 1.
Study data collection
| Study characteristic | Specific items |
|---|---|
| Study identifiers | Title, authors, journal, publication year, county of publication, and sponsorship |
| Study design | Number of animals assigned to each experimental and control group and method of SNHL induction |
| Animal model characteristics | Animal species, gender, strain, age, method of SNHL induction, and immune status |
| Intervention characteristics | Source of MSCs, MSC identifiers including plastic adherence, positive/negative markers, differentiation, cell expansion media, passage number, cell dose, method of delivery, timing relative to SNHL induction, and frequency of MSC administration |
| Outcome measures | Method of assessing hearing outcome and timing of data collection relative to SNHL induction |
| Other | Long-term outcomes, type of control, MSC side effects (animal survival) |