Table 3.
Comparison of the patients according to MDA median (3.90 nmol/mL) in the study group
| MDA<3.90 nmol/mL (n=26) |
MDA≥3.90 nmol/mL (n=27) |
p | |
| Male n (%) | 18.00 (69.20) | 16.00 (59.30) | 0.449 |
| Age (years) | 65.27±9.71 | 64.70±11.61 | 0.887 |
| Diabetes duration (years) | 8.50 (6.00-12.00) | 8.00 (6.00-18.00) | 0.810 |
| Waist circumference (cm) | 107.73±14.91 | 109.22±12.34 | 0.693 |
| BMI (kg/m2) | 31.22±6.29 | 32.89±5.63 | 0.313 |
| Total cholesterol (mg/dL) | 180.00 (153.00-219.00) | 203.00 (155.00-229.50) | 0.520 |
| HDL cholesterol (mg/dL) | 45.27±10.44 | 43.85±14.43 | 0.685 |
| Triglycerides (mg/dL) | 132.50 (94.00-199.00) | 142.00 (105.00-223.00) | 0.444 |
| LDL cholesterol (mg/dL) | 107.74±39.80 | 105.90±45.03 | 0.915 |
| CRP (mg/dL) | 0.25 (0.17-0.36) | 0.37 (0.20-0.61) | 0.301 |
| Serum glucose (mg/dL) | 136.79 (125.95-180.12) | 143.81 (128.63-168.33) | 0.896 |
| HbA1C (%) | 7.00 (6.50-8.30) | 7.82 (7.00-9.80) | 0.030 |
| eGFR (mL/min/1.73m2) | 92.27 (71.57-102.35) | 83.11 (52.59-94.84) | 0.255 |
| UACR (mg/g) | 18.08 (4.06-72.60) | 13.09 (4.88-26.39) | 0.226 |
| MDA (nmol/mL) | 2.67±0.71 | 5.28±1.06 | |
| SOD (U/g) | 654.21±98.12 | 585.68±165.85 | 0.028 |
| CAT (U/g) | 3.39 (2.53-3.49) | 2.91 (2.68-3.38) | 0.378 |
| uACE2 | 57.15 (40.30-71.20) | 38.50 (31.80-45.95) | <0.001 |
| CVDSc n (%) | 0.00 (00.00-0.00) | 1.00 (0.00-1.50) | 0.002 |
Legend n - number of patients, BMI - body mass index, HDL- high density lipoprotein, LDL- low density lipoprotein, CRP - C reactive protein, HbA1c - glycated haemoglobin, eGFR - estimated glomerular filtration rate, UACR- urinary albumin to creatinine ratio, MDA - malondialdehyde, SOD - superoxide dismutase, CAT- catalase, uACE2 - urinary angiotensin converting enzyme 2, CVDSc – cardiovascular disease score. Values are expressed as mean ± standard deviation for normally distributed variables and median (interquartile range) for non-normally distributed ones.