Table 2.

Adenosine diphosphate, protease-activated receptor 4 agonist, and arachidonic acid-induced platelet aggregation in diabetic and control rats

Parameter	Control (n = 6)	Diabetes (n = 5)	p-value
ADP-induced aggregation (AUC; AU)	67.7 ± 2.5	58.2 ± 2.0	0.04
PAR4 agonist-induced aggregation (AUC; AU)	63.5 ± 2.0	62.6 ± 1.4	1.00
AA-induced aggregation (AUC; AU)	59.3 ± 2.3	45.0 ± 0.9	< 0.01

AA – arachidonic acid; ADP – adenosine diphosphate; AU – arbitrary units; AUC – area under the curve; PAR4 – protease-activated receptor 4. Data are expressed as means ± standard error of the mean. p-values refer to between-group comparisons using the Mann-Whitney U test.