Table 2.
Comparison of some echocardiographic markers between the male patient groups and their corresponding control groups
| Males |
Group1 (N=6) |
Control1 (N=6) |
p |
Group2 (N=16) |
Control2 (N=16) |
p |
Group3 (N=18) |
Control3 (N=18) |
p |
Group4 (N=16) |
Control4 (N=16) |
p |
| ivstd | 13±2.5 | 12±0.9 | 0.105 | 13.7±1.8 | 13.6±0.8 | 0.439 | 13±3.4 | 12±1.3 | 0.251 | 13.7±2.5 | 13.9±0.9 | 0.543 |
| lvidd | 46.7±10.5 | 50.2±3.9 | 0.777 | 45.8±8.7 | 48.8±3.7 | 0.218 | 51.5±5.6 | 49.6±2.7 | 0.524 | 49.7±5 | 51±3.7 | 0.284 |
| pwtd | 12.2±2.3 | 11.3±1.4 | 0.425 | 12.8±1.2 | 13.1±0.7 | 0.359 | 12.7±2.5 | 11.8±1.3 | 0.292 | 13.2±1.5 | 12.9±0.9 | 0.435 |
| ivsts | 17.4±3.3 | 17.3±1.2 | 0.810 | 18.9±2.4 | 17.6±0.9 | 0.005 | 17.1±4.2 | 16.4±3.4 | 0.774 | 18.5±2.1 | 16.9±1.1 | 0.026 |
| lvids | 32±7.6 | 33.7±3.4 | 0.608 | 29.2±7 | 30.1±3.9 | 0.513 | 33.7±6.4 | 31.7±3.6 | 0.276 | 31.4±4.8 | 31.8±4.1 | 0.619 |
| pwts | 19.6±3.6 | 18.5±1 | 0.003 | 20.3±3 | 17.8±1.2 | 0.006 | 18.6±5 | 18.6±5 | 1.000 | 20.7±3.3 | 18.8±2.6 | 0.079 |
| la | 38.6±4.3 | 37.2±1.5 | 0.351 | 40.3±5.9 | 38.3±2.3 | 0.300 | 42.8±6.5 | 36±2.5 | 0.000 | 40.7±5.7 | 37.8±3.7 | 0.062 |
| ao | 37.5±4.5 | 37.2±1.7 | 0.016 | 39.1±3.7 | 37.9±1.1 | 0.337 | 39.4±4.9 | 36.4±2.5 | 0.082 | 40.4±5.9 | 36.9±2.9 | 0.048 |
| ef | 66.1±5 | 62.5±5.7 | 0.759 | 68.8±9.6 | 72.7±7.3 | 0.117 | 63.4±9.2 | 69.2±7.4 | 0.069 | 64.4±10.2 | 66.1±4.3 | 0.843 |
| efs | 36.4±3.3 | 38.8±3.4 | 0.150 | 42.2±7.7 | 39.8±3.2 | 0.473 | 35.9±6.5 | 36.3±3.4 | 0.972 | 38.5±3.6 | 37.9±2.1 | 0.553 |
| lvm | 272.1±94.8 | 224±32 | 0.083 | 301.7±81.9 | 264.9±50.2 | 0.170 | 310.2±143.7 | 230.8±43.1 | 0.060 | 296.4±120.2 | 283.8±39.4 | 0.664 |
| lvm index | 150.8±32.7 | 110±17 | 0.04 | 142.2±38.9 | 123.8±19.5 | 0.135 | 138.9±54.4 | 105±18 | 0.037 | 132.4±42.5 | 127.6±23.1 | 0.477 |
| dte | 251.5±48 | 188.7±12.9 | 0.006 | 275±48.5 | 223.8±34.6 | 0.003 | 226.1±80.9 | 193.2±15.4 | 0.023 | 234.4±61.5 | 201±19 | 0.002 |
| ivrt | 126.9±27.1 | 105.2±9.3 | 0.136 | 118.1±24.5 | 116±18.1 | 0.719 | 102.5±24.6 | 118.7±22.9 | 0.056 | 118.2±29.4 | 120.8±20.8 | 0.921 |
| tric e | 0.4±0.1 | 0.6±0.1 | 0.004 | 0.5±0.1 | 0.6±0.1 | 0.041 | 0.5±0.1 | 0.5±0.1 | 0.201 | 0.5±0.1 | 0.6±0.1 | 0.109 |
| tric a | 0.3±0.1 | 0.6±0.1 | 0.001 | 0.3±0.1 | 0.6±0.1 | 0.000 | 0.4±0.2 | 0.5±0.1 | 0.106 | 0.4±0.1 | 0.5±0.1 | 0.005 |
| tric dt | 227.2±36.6 | 190.3±10.8 | <0.001 | 269.1±39.9 | 253.8±42.4 | 0.336 | 210.7±69.7 | 223.7±47.4 | 0.826 | 221.4±54 | 192.9±52.6 | 0.062 |
| TDV | 108.4±41.3 | 127.8±29.3 | 0.824 | 106±37.4 | 116.8±26 | 0.152 | 124.7±36.2 | 128.7±26 | 0.303 | 112.1±26.9 | 128.1±25.9 | 0.043 |
| TSV | 37.9±20.1 | 54.2±12.6 | 0.481 | 31.9±12.8 | 28±7.2 | 0.428 | 45.9±17.6 | 34±11.4 | 0.032 | 38.5±13.1 | 34.4±13.8 | 0.196 |
| SV | 70.6±22.1 | 75.2±29.3 | 0.887 | 74.1±25.2 | 88.8±23.7 | 0.050 | 78.8±25 | 95.2±24.8 | 0.029 | 64.4±30.6 | 93.3±23.5 | 0.006 |
| la_index | 18.9±2.3 | 17.9±1.7 | 0.558 | 19.3±4.1 | 18.1±2.1 | 0.353 | 19.6±2.4 | 16.5±1.6 | 0.000 | 18.6±2.4 | 16.9±2.1 | 0.048 |
| ao_index | 19.6±1.6 | 17.9±1.4 | 0.134 | 18.7±2.6 | 17.8±1.3 | 0.678 | 18.1±2.5 | 16.6±1.1 | 0.011 | 18.4±1.9 | 16.6±2.1 | 0.026 |
| TDV_index | 63.9±21.2 | 61.9±16.6 | 0.663 | 50±16.5 | 54.8±11.7 | 0.206 | 56.9±15.1 | 58.9±13 | 0.527 | 50.6±8 | 57.8±15.1 | 0.262 |
| TSV_index | 25.3±11.5 | 25.9±5.7 | 0.919 | 15±5.7 | 13.1±3.3 | 0.553 | 21.1±8 | 15.4±4.7 | 0.029 | 17.4±4.7 | 15.5±6.4 | 0.114 |
| SV_index | 40.6±10.2 | 36.7±15.5 | 0.500 | 35±11.1 | 41.6±10.5 | 0.030 | 35.8±10.3 | 43.7±12.6 | 0.034 | 33.3±6.3 | 42.1±12.8 | 0.067 |
| e/a | 1.6±0.3 | 1.2±0.1 | 0.009 | 1.5±0.3 | 1±0.3 | 0.001 | 1.3±0.3 | 1.2±0.3 | 0.246 | 1.3±0.3 | 1.1±0.3 | 0.255 |
Group 1 – normotensive patients with controlled acromegaly; group 2 –hypertensive patients with controlled acromegaly; group 3- normotensive patients with active acromegaly; group 4 – hypertensive patients with active acromegaly p- value of significance; significant results are bolded; ivstd - end-diastolic interventricular septum thickness; lvidd - left ventricular internal end-diastolic diameter; pwtd – posterior wall thickness in diastole; ivsts - end-systolic interventricular septum thickness; lvids - left ventricular internal end-systolic diameter; pwts – posterior wall thickness in systole; la – left atrium diameter; ao – maximum aortic diameter; ef – ejection fraction; efs – shortening fraction; lvm – left ventricular mass; lvm_index – left ventricular mass index; dte – deceleration time; ivrt - isovolumetric relaxation time; tric e – tricuspidal early filling; tric a – tricuspidal atrial contraction; tric dt – deceleration time of the right ventricle; TDV – telediastolic volume; TSV – telesystolic volume; SV – stroke volume; la_index - left atrium diameter index; ao _index - maximum aortic diameter index; TDV_index - telediastolic volume index; TSV_index - telesystolic volume index; SV_index – stroke volume index; e/a – early filling atrial contraction ratio