Table 3.
Comparison of some echocardiographic markers between the female patient groups and their corresponding control groups
| Females |
Group1 (N=15) |
Control1 (N=15) |
p |
Group2 (N=26) |
Control2 (N=26) |
p |
Group3 (N=18) |
Control3 (N=18) |
p |
Group4 (N=31) |
Control4 (N=31) |
p |
| ivstd | 11.1±2.6 | 11.1±1.3 | 0.816 | 13.1±2.1 | 13.3±0.8 | 0.669 | 10.2±3.4 | 9.6±1.9 | 0.987 | 13.1±2.3 | 13.8±1 | 0.070 |
| lvidd | 44.4±6.5 | 47.2±4.4 | 0.243 | 42.7±8.3 | 45.4±3.5 | 0.175 | 44.7±3.4 | 26.7±3.4 | <0.001 | 45.6±5.7 | 35.3±5.4 | <0.001 |
| pwtd | 10.2±2.2 | 10.9±1.5 | 0.198 | 13.5±6.2 | 12.8±1 | 0.418 | 10.1±2.2 | 9.2±0.9 | 0.095 | 12.4±2.1 | 14.1±0.8 | <0.001 |
| ivsts | 15.6±2.6 | 15.7±2.4 | 0.807 | 17.1±3 | 15.6±1.5 | 0.092 | 15.3±2.7 | 10.6±1.3 | <0.001 | 17.1±2.6 | 19.3±1.9 | 0.001 |
| lvids | 31.7±9.6 | 29.7±2.4 | 0.553 | 26.9±5.7 | 26.9±5.7 | 1.000 | 27.1±3.9 | 38.6±4.9 | <0.001 | 28.2±4.3 | 47.8±4 | <0.001 |
| pwts | 19±3 | 18.8±2.2 | 0.894 | 19.3±3 | 16.5±1.7 | <0.001 | 18.7±4.6 | 11.2±0.8 | <0.001 | 19±2.9 | 18.3±1.5 | 0.220 |
| la | 34.9±6.1 | 34.5±3.1 | 0.597 | 38.8±5.3 | 36.8±3.8 | 0.070 | 35.4±6 | 33.5±2.7 | 0.589 | 38.2±6.4 | 33.7±2.7 | 0.001 |
| ao | 34.8±6.9 | 34.8±6.9 | 1.000 | 34.2±3.5 | 33.5±2.2 | 0.617 | 31.9±2.4 | 33.3±1.8 | 0.029 | 34.4±4.3 | 33±2 | 0.128 |
| ef | 67±10.9 | 70.5±4.7 | 0.803 | 67.8±7.5 | 66.8±5.4 | 0.238 | 71.1±4.1 | 63.3±6.3 | <0.001 | 68.1±5.9 | 64.6±4.2 | 0.017 |
| efs | 41.1±7.9 | 40.3±6.8 | 0.328 | 37.9±5.3 | 38.3±4.8 | 0.415 | 40.5±3.2 | 36.9±2.5 | 0.001 | 38.6±6.8 | 35.6±2.7 | 0.048 |
| lvm | 204.3±68.1 | 181.7±38.5 | 0.407 | 237±77.6 | 228.8±30.1 | 0.770 | 178.2±78.9 | 111.9±35.3 | 0.006 | 252±107.1 | 272.1±40.6 | 0.025 |
| lvm index | 105.2±25.6 | 100.6±18.5 | 0.570 | 120.7±35.4 | 122.1±16.2 | 0.372 | 96.6±38.7 | 62.8±23.2 | 0.005 | 130±46.9 | 148.6±26.3 | 0.011 |
| dte | 231.3±49.4 | 217.9±39.2 | 0.350 | 255±63.9 | 213.8±40 | 0.005 | 215±54.9 | 182.6±10.9 | 0.003 | 258.4±70.3 | 189.9±14.4 | <0.001 |
| ivrt | 94.8±15.5 | 97.7±12.8 | 0.225 | 119.2±20.1 | 112.7±18.8 | 0.411 | 91.7±17.4 | 75.6±9.7 | 0.010 | 113.9±24.9 | 110±32.7 | 0.344 |
| tric e | 0.5±0.1 | 0.6±0.1 | 0.001 | 0.5±0.1 | 0.5±0.1 | 0.001 | 0.5±0.1 | 0.7±0.1 | <0.001 | 0.4±0.1 | 0.7±0.1 | <0.001 |
| tric a | 0.3±0.1 | 0.4±0.1 | 0.023 | 0.4±0.1 | 0.4±0.1 | 0.101 | 0.4±0.1 | 0.6±0.1 | <0.001 | 0.3±0.1 | 0.6±0.1 | <0.001 |
| tric dt | 237.1±57.3 | 209.2±36.8 | 0.191 | 252.2±61.1 | 182.7±33.4 | <0.001 | 215.1±48.7 | 182.5±17.4 | 0.003 | 238.9±54.7 | 175.4±32.6 | <0.001 |
| TDV | 105.5±24.3 | 107.8±28.1 | 0.819 | 89.6±31.2 | 95.4±22 | 0.317 | 91.8±15.7 | 63.4±24.2 | 0.001 | 98.3±28.3 | 109.9±26.7 | 0.082 |
| TSV | 32.5±9.1 | 28.9±10.8 | 0.092 | 30.5±16.4 | 25.8±15.7 | 0.210 | 26.6±7.4 | 20.5±7.3 | 0.008 | 32.4±11.5 | 37±15.5 | 0.461 |
| SV | 73±17.6 | 78.9±26.2 | 0.406 | 59.2±19 | 68.8±21.9 | 0.055 | 64.2±9.7 | 41.6±19.1 | 0.001 | 65.9±19.3 | 72.9±20.2 | 0.173 |
| la_index | 18.2±1.7 | 18.5±1.3 | 0.678 | 20.5±2.7 | 19.6±2.2 | 0.244 | 19.5±3 | 18.7±2.4 | 0.411 | 20±3.6 | 18.4±1.9 | 0.038 |
| ao_index | 18.3±3.5 | 18.6±3.8 | 0.709 | 18.3±2.3 | 17.9±1.9 | 0.522 | 17.7±1.9 | 18.6±1.8 | 0.235 | 18±2.6 | 18.1±1.8 | 0.838 |
| TDV_index | 55.6±14.2 | 57.7±14.9 | 0.694 | 45.5±14.3 | 50.8±11 | 0.100 | 50.5±8.4 | 35.8±15.1 | 0.006 | 51.4±14.4 | 60.3±15.4 | 0.037 |
| TSV_index | 17.1±4.7 | 15.3±5 | 0.165 | 15.6±8 | 13.7±8.3 | 0.253 | 14.6±3.6 | 11.7±5 | 0.017 | 16.9±5.7 | 20.2±8.2 | 0.273 |
| SV_index | 38.6±10.5 | 42.4±14.3 | 0.372 | 29.9±8.6 | 36.7±11.6 | 0.024 | 35.6±6 | 23.6±11.6 | 0.004 | 34.5±10 | 40.1±12.3 | 0.059 |
| e/a | 1.5±0.4 | 1.7±0.4 | 0.290 | 1.3±0.3 | 1.4±0.4 | 0.516 | 1.4±0.4 | 1.3±0.2 | 0.086 | 1.3±0.3 | 1.2±0.4 | 0.012 |
Group 1 – normotensive patients with controlled acromegaly; group 2 – hypertensive patients with controlled acromegaly; group 3- normotensive patients with active acromegaly; group 4 – hypertensive patients with active acromegaly; p – value of significance; significant results are bolded; ivstd - end-diastolic interventricular septum thickness; lvidd - left ventricular internal end-diastolic diameter; pwtd – posterior wall thickness in diastole; ivsts - end-systolic interventricular septum thickness; lvids - left ventricular internal end-systolic diameter; pwts – posterior wall thickness in systole; la – left atrium diameter; ao – maximum aortic diameter; ef – ejection fraction; efs – shortening fraction; lvm – left ventricular mass; lvm_index – left ventricular mass index; dte – deceleration time; ivrt - isovolumetric relaxation time; tric e – tricuspidal early filling; tric a – tricuspidal atrial contraction; tric dt – deceleration time of the right ventricle; TDV – telediastolic volume; TSV – telesystolic volume; SV – stroke volume; la_index - left atrium diameter index; ao _index - maximum aortic diameter index; TDV_index - telediastolic volume index; TSV_index - telesystolic volume index; SV_index – stroke volume index; e/a – early filling atrial contraction ratio.