Examples of 4 VCY measures, each representing the VCY based on VLs measured in the 1 year and 3 years immediately following cART initiation (VCY from cART) and VCY based on VLs measured in the most recent 1 year and 3 years (Recent VCY), respectively, for an individual with VLs at 20 study visits and a follow-up time of 9.8 years following cART initiation.
Top, time-updated VL measurements from study visit 1 to visit 20. Arrows represent the time periods used to assess each of the 4 VCY measures at visit 20 (V20). Shaded areas represent the values of each of the 4 VCY measures at visit 20.
Bottom, time-updated values for the 4 VCY measures from study visit 1 to visit 20.
Abbreviations: VCY, viremia copy-years; VL, viral load; cART, combination antiretroviral therapy