Table 2.
The distributions of viremia copy-year and cross-sectional viral load measurements, and the proportions of individuals who maintained virologic suppression during various time periods after cART initiation.
| Time periods | Names of VCY or VL measurements | Log10 median (IQR) of VCY or VL measures* | % Virally suppressed† |
|---|---|---|---|
| Last pre-cART visit | Last pre-cART VL | 4.5 (3.9–5.1) | 5 |
| Most recent visit | Most recent VL | 1.6 (1–2) | 72 |
| First visit after cART | First VL after cART | 1.9 (1.6–3) | 44 |
| Entire follow-up from cART | Overall VCY | 4.3 (3.6–4.9) | 33 |
| First year from cART | VCY from cART, 1y | 3.9 (3.3–4.4) | 55 |
| Initial 2 years from cART | VCY from cART, 2y | 4 (3.4–4.6) | 46 |
| Initial 3 years from cART | VCY from cART, 3y | 4.1 (3.5–4.6) | 42 |
| Initial 4 years from cART | VCY from cART, 4y | 4.1 (3.5–4.7) | 40 |
| Initial 5 years from cART | VCY from cART, 5y | 4.2 (3.5–4.7) | 38 |
| Initial 6 years from cART | VCY from cART, 6y | 4.2 (3.6–4.8) | 37 |
| Initial 7 years from cART | VCY from cART, 7y | 4.2 (3.6–4.8) | 36 |
| Initial 8 years from cART | VCY from cART, 8y | 4.2 (3.6–4.8) | 35 |
| Initial 9 years from cART | VCY from cART, 9y | 4.2 (3.6–4.9) | 34 |
| Initial 10 years from cART | VCY from cART, 10y | 4.2 (3.6–4.9) | 34 |
| Recent 1 year | Recent VCY, 1y | 1.6 (1–3.5) | 69 |
| Recent 2 years | Recent VCY, 2y | 2.2 (1.5–4.1) | 61 |
| Recent 3 years | Recent VCY, 3y | 3.1 (1.8–4.3) | 55 |
| Recent 4 years | Recent VCY, 4y | 3.4 (2.1–4.4) | 50 |
| Recent 5 years | Recent VCY, 5y | 3.6 (2.2–4.5) | 47 |
| Recent 6 years | Recent VCY, 6y | 3.7 (2.4–4.5) | 46 |
| Recent 7 years | Recent VCY, 7y | 3.8 (2.4–4.6) | 44 |
| Recent 8 years | Recent VCY, 8y | 3.8 (2.6–4.6) | 43 |
| Recent 9 years | Recent VCY, 9y | 3.9 (2.8–4.7) | 41 |
| Recent 10 years | Recent VCY, 10y | 4 (3–4.7) | 40 |
Values of the overall VCY, 10 recent VCY measures and the most recent VL were determined at the last follow-up visit in this study.
Viral suppression was defined as consistent VL measurements below the assay-specific level of detection, except for a single blip of <400 copies/mL.
Values of the VCY measures in the first 1 to 10 years following cART were determined at the end of the respective time periods.
Abbreviations: cART, combination antiretroviral therapy; VCY, viremia copy-years; VL, viral load; cART, combination antiretroviral therapy; IQR, interquartile range