Table 1.

Severity of Infectious Mononucleosis Scale

Severe symptoms a:

_____ Pharyngitis to the point where can’t swallow even liquids

_____ Headache so severe as to prompt an LP or neuroimaging

_____ Fever > 104ºF for > 2 weeks

_____ Fever > 101ºF for > 5 weeks

_____ Not able to leave home during worst symptoms

_____ Reduced walking distance during worst symptoms

_____ Trouble breathing

_____ GI symptoms (anorexia, nausea, vomiting: NOT Diarrhea alone)

Severe Physical Examination findings:

_____ Jaundice

_____ ”Bull neck” (prominent, warm, tender bilateral cervical adenopathy with edema)

_____ Painfully enlarged spleen

_____ Painfully enlarged liver

_____ Palatal petechiae

Complications b:

_____ Cardiac (e.g., myocarditis)

_____ Hematologic (e.g., thrombocytopenia (<150,000/mm3), neutropenia (<1000/mm3), lymphopenia (<2000/mm3), hemolytic anemia, hemophagocytic lymphohistiocytosis)

_____ Neurologic (e.g., meningoencephalitis)

_____ Pulmonary (e.g., pleural effusion, pneumonitis)

^aEach sign, symptom or complication present scores a 1

^bDo not count the same sign or symptom more than once (e.g., if trouble breathing due to pleural effusion, count one or the other but not both)