Platelet prothrombinase activity mediated by the combined synergistic
effect of shear stress activation and EC inflammatory cytokine activation. 30P,
50P and 70P indicate 30 dynes/cm2, 50 dynes/cm2 and 70
dynes/cm2 shear-activated platelets, respectively; ECs, 10ECs and
100ECs indicate nonactivated, 10 ng/mL and 100 ng/mL TNF-α-activated ECs,
respectively. Data are reported as mean ± SD. * p<0.05; ***
p<0.001.