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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Heart Lung Transplant. 2019 Feb 18;38(6):658–667. doi: 10.1016/j.healun.2019.02.009

Figure 5:

Figure 5:

Proposed schema of prothrombotic interaction between inflamed ECs and shear-activated platelets in the LVAD-implanted ventricle. (A) the LVAD-implanted ventricle; (B) cross-sectional view of the LVAD-implanted ventricular apex: here, shear-activated circulating platelets that follow secondary/peripheral blood flow not entering the LVAD inflow cannula accumulate and get trapped, facing with (C) inflammatory activated endocardial endothelial cells (ECs), with associated integrin-mediated platelet adherence and apposition on the LVAD inflow cannula.