TABLE 2.
Treatment regimen
| Group | Intervention | Frequency (no. of daily doses) | Daily dose |
|---|---|---|---|
| A | Untreated control at the start of treatment (day 28) | ||
| B | Untreated control at the end of treatment (day 57) | ||
| C | Oral ETO and DCS at human equivalent dose for 4 weeks | 20 | 4.7 mg ETO + 2.35 mg DCS |
| D | Inhaled ETO and DCS for 4 weeks | 20 | 70 μg ETO + 35 μg DCS |
| E | Oral ETO and DCS at inhalation-equivalent dose for 4 weeks | 20 | 70 μg ETO +35 μg DCS |
| F | Inhaled + oral to achieve human equivalent dose | 20 | 4.63 mg ETO + 2.31 mg DCS (oral); 70 μg ETO +35 μg DCS (inhalation) |