FIG 5.
Schematic representations of plasmid pAQZ1 containing qacA4 obtained from the de novo assemblies of isolates 91.2 and 107.2 (a), plasmid pAQZ2 retained in isolate 107.2cured (b), and the 11,934-bp segment of pAQZ1 eliminated through the curing experiments (c). Open reading frames (ORFs) shown in red depict resistance genes, ORFs in orange describe heavy metal efflux genes, ORFs in green represent transcriptional regulator genes, ORFs in blue depict recombinase genes, ORFs in purple describe replication genes, ORFs in white represent hypothetical proteins, and ORFs in yellow depict genes with other functions.