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Quantification of drug exposure in lung lesions and nonlesion areas. The isavuconazole concentration was measured in lesions and nonlesion areas dissected from lung sections collected 1, 3, 6, and 24 h after a single oral dose of isavuconazonium sulfate at 256 mg/kg. Error bars show means ± standard deviations (SD) from 3 lung sections.
