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. 2019 May 21;12:4001–4011. doi: 10.2147/OTT.S195826

Figure 5.

Figure 5

The cell proliferation and cell apoptosis influenced by HEATR1 and p53 inhibition in A549 and HCI-H460 cells. (A) MTT assay. Cell proliferation was significantly increased in cells transduced with both shHEATR1 and shp53 compared to cells transduced with shHEATR1 lentivirus (P<0.05). (B) Apoptosis assay. The percentage of apoptosis was significantly reduced in cells transduced with both shHEATR1 and shp53 compared to cells transduced with shHEATR1 lentivirus (P<0.001). N=3. Values were expressed as mean ± standard deviation. * P<0.05, ** P<0.01, *** P<0.001, compared to shHEATR1 group.