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. 2019 May 20;14:3615–3627. doi: 10.2147/IJN.S190830

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© 2019 Hamidu et al.

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Morphology of MCF-7 cells treated for 48 hrs with DOX as well as doxorubicin nanoparticles (DOX-NPs). (A) Control cells (untreated). (B) Cells treated with free NPs. (C) Cells treated with DOX. (D) Cells treated with DOX-NPs. Red indicators portray cell shrinkage with detachment; yellow arrows portray DOX-NPs coacervates (scale bar: 100 µm).