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. 2019 May 23;11:1758835919850665. doi: 10.1177/1758835919850665

Figure 4.

Figure 4.

MiR-193a inhibited non-small cell lung carcinoma (NSCLC) cell proliferation and invasion and promotes NSCLC cell apoptosis by targeting epidermal growth factor receptor (EGFR). A549 cells were transfected with miR-NC, miR-193a mimic (miR-193a), anti-miR-NC, miR-193a inhibitor (anti-miR-193a), miR-NC plus control plasmid (control), miR-193a mimic plus control plasmid (miR-193a), miR-NC plus EGFR overexpression plasmid (EGFR), or miR-193a mimic plus EGFR overexpression plasmid (miR-193a+EGFR). (a, e) Representative images and histogram statistics from cell proliferation assays (EdU). (b, f) Transwell analysis of invaded A549 cells. (c, g) Cell apoptosis assays were performed after the transfection. (d, h) Cell proliferation assays (CCK-8) were performed 12, 24, 48, 72, and 96 h after the transfection. *p < 0.05, **p < 0.01, ***p < 0.001.