Table 3.
Diagnostic Performances of Logistic Regression Model in Training Set and Validation Sets.
| Group | AFP-Negative Patients With HCC vs Healthy controls | ||||
|---|---|---|---|---|---|
| AUC | 95% CI | P Value | Se (%) | Sp (%) | |
| Training set | |||||
| Zhongnan Hospital | 0.922 | 0.892-0.957 | <.0001 | 83.0 | 93.1 |
| Validation sets | |||||
| Zhongnan Hospital | 0.860 | 0.801-0.919 | <.0001 | 80.2 | 92.5 |
| Tongji Hospital | 0.839 | 0.752-0.926 | <.0001 | 78.3 | 88.9 |
| Xiehe Hospital | 0.857 | 0.766-0.949 | <.0001 | 81.6 | 89.5 |
| Renmin Hospital | 0.901 | 0.841-0.960 | <.0001 | 87.7 | 92.3 |
Abbreviations: AFP, α-fetoprotein; AUC, area under the curve; CI, confidence interval; HCC, hepatocellular carcinoma; Se, sensitivity; Sp, specificity