Table 4.

Haematological findings in male rats treated with ruthenium baicalein complex for 28 days

Parameters	Control	Ru-B50 mg/kg	Ru-B100 mg/kg	Ru-B200 mg/kg	Ru-B400 mg/kg
Aspartate aminotransferase (AST)	51.23 ± 7.89	51.87 ± 9.61	51.92 ± 9.31	55.87 ± 8.17	109.97 ±7.17*
Alanine aminotransferase (ALT)	37.21 ± 2.14	37.52 ± 2.34	38.99 ± 2.25	40. 17 ± 0.02	99.92 ± 10.21*
Alkaline phosphatase (ALP)	78.15 ± 15.12	66.27 ± 15.12	78.89 ± 15.48	61.17 ± 33.85	101.00 ± 56.07*
Total protein (g/dl)	5.45 ± 0.16	6.72 ± 0.18	6.84 ± 0.20	6.19 ± 0.14	2.17 ± 0.32*
Albumin (g/dl)	4.02 ± 0.16	3.92 ± 0.21	3.85 ± 0.09	3.48 ± 0.22	6.17 ± 0.07*
Globulin (g/dl)	4.08 ± 0.16	4.02 ± 0.15	3.92 ±0.03	3.78 ± 0.23	4.07 ± 0.13
Total bilirubin (mg/dl)	0.47 ± 0.06	0.42 ± 0.08	0.59 ± 0.12	0.49 ± 0.09	2.12 ± 0.03*
Blood urea nitrogen (mg/dl)	15.27 ± 2.98	17.06 ± 2.87	15.88 ± 2.37	15.87 ± 2.96	28.89 ± 1.16*
Creatinine (mg/dl)	0.59 ± 0.09	0.63 ± 0.13	0.60 ± 0.09	0.62 ± 0.22	1.59 ± 0.19*

Standard error mean = standard deviation (SD)/√Total subject. Results were analysed by t test and one-way ANOVA and confirmed by Dunett's multiple comparison tests. MCV- mean corpuscle value, MCH- mean corpuscle haemoglobin, MCHC- mean corpuscle haemoglobin concentration, RBC- red blood cell, WBC- white blood cell. * p<0.05 significant difference when compared to the control group.