Table 5.
Haematological findings in female rats treated with ruthenium baicalein complex for 28 days
| Parameters | Control | Ru-B50 mg/kg | Ru-B100 mg/kg | Ru-B200 mg/kg | Ru-B400 mg/kg |
|---|---|---|---|---|---|
| Haemoglobin (Gm%) | 11.92 ± 0.06 | 11.98 ± 0.079 | 12.27 ± 0.05 | 12.42 ± 0.06 | 12.58 ± 0.01 |
| Total RBC count (×106 / µl) | 4.43 ± 0.011 | 4.47 ± 0.012 | 4.43 ± 0.018 | 4.27 ± 0.04 | 4.38 ± 0.011 |
| WBC count (×103 / µl) | 4.98 ± 0.38 | 5.22 ± 0.19 | 5.34 ± 0.13 | 5.41 ± 0.11 | 13.21 ± 0.06* |
| Platelet count (×105 / µl) | 6.08 ± 0.48 | 6.01 ± 0.24 | 6.88 ± 0.27 | 6.13 ± 0.39 | 6.15 ± 0.19 |
| MCV (fL) | 90.12 ± 1.08 | 91.06 ± 1.13 | 91.22 ± 1.42 | 91.57 ± 1.16 | 90.97 ± 1.13 |
| MCH (pg) | 29.17 ± 0.09 | 29.31 ± 0.10 | 28.31 ± 0.16 | 27.93 ± 0.09 | 29.02 ± 0.04 |
| MCHC (%) | 31.71 ± 0.41 | 31.93 ± 0.62 | 31.27 ± 0.18 | 32.92 ± 0.29 | 31.94 ± 0.23 |
| Neutrophil (%) | 51.62 ± 0.11 | 56.35 ± 0.06 | 47.11 ± 0.15 | 46.32 ± 0.32 | 53.06 ± 0.11 |
| Eosinophil (%) | 2.16 ± 0.17 | 2.25 ± 0.24 | 3.09 ± 0.25 | 2.54 ± 0.12 | 2.21 ± 0.15 |
| Basophil (%) | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
| Lymphocyte (%) | 34.19 ± 1.14 | 34.08 ± 2.06 | 29.27 ± 1.11 | 30.05 ± 1.06 | 34.16 ± 1.58 |
| Monocyte (%) | 3.78 ± 0.74 | 3.61 ± 0.65 | 3.62 ± 0.59 | 3.61 ± 0.47 | 2.84 ± 0.83 |
Standard error mean = standard deviation (SD)/√Total subject. Results were analysed by t test and one-way ANOVA and confirmed by Dunett's multiple comparison tests. MCV- mean corpuscle value, MCH- mean corpuscle haemoglobin, MCHC- mean corpuscle haemoglobin concentration, RBC- red blood cell, WBC- white blood cell. * p<0.05 significant difference when compared to the control group.