Table 7.

Serum biochemical findings in female rats treated with ruthenium baicalein complex for 28 days

Parameters	Control	Ru-B50 mg/kg	Ru-B100 mg/kg	Ru-B200 mg/kg	Ru-B400 mg/kg
Aspartate aminotransferase (AST)	48.62 ± 9.84	58.12 ± 9.88	44.24 ± 13.15	48.53 ± 13.56	104.36 ± 24.45*
Alanine aminotransferase (ALT)	38.56 ± 4.54	37.45 ± 3.58	40.46 ± 1.94	42.18 ± 4.96	97.92 ± 6.42*
Alkaline phosphatase (ALP)	68.51 ± 24.59	74.63 ± 16.24	85.62 ± 9.31	90.53 ± 1.92	148.64 ± 41.58*
Total protein (g/dl)	6.57 ± 0.14	6.15 ± 0.18	6.75 ± 0.14	6.45 ± 0.11	3.74 ± 0.75*
Albumin (g/dl)	4.04 ± 0.18	3.84 ± 0.12	3.48 ± 0.15	3.99 ± 0.01	5.95 ± 0.44*
Globulin (g/dl)	2.85 ± 0.18	2.75 ± 0.35	2.46± 0.25	2.48 ± 0.48	2.59 ± 0.14
Total bilirubin (mg/dl)	0.24 ± 0.04	0.28 ± 0.04	0.35 ± 0.01	0.38 ± 0.1	1.64 ± 0.14*
Blood urea nitrogen (mg/dl)	15.23 ± 2.15	14.54 ± 2.16	14.58 ± 2.15	15.45 ± 2.14	27.34 ± 1.47*
Creatinine (mg/dl)	0.65 ± 0.10	0.64 ± 0.02	0.65 ± 0.04	0.67 ± 0.05	2.01 ± 0.14*

Standard error mean = standard deviation (SD)/√Total subject. Results were analysed by t test and one way ANOVA and confirmed by Dunett's multiple comparison tests. * p<0.05 significant difference when compared to the control group.