Table 8.
Groups | No. of crypts/ACF | Total number of ACF | ||||
---|---|---|---|---|---|---|
Crypt 1 | Crypt 2 | Crypt 3 | Crypt 4 | Crypt 5 | ||
Control | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
DMH + DSS | 25 ± 7.12 | 32 ± 6.53 | 44 ± 8.37 | 38 ± 2.2 | 35 ± 7.32 | 174 ± 31.54 |
DMH + DSS + Ru-B 50 mg/kg | 10 ± 0.3 | 14 ± 5.2 | 18 ± 5.7 | 12 ± 4.1 | 10 ± 2.5 | 64 ± 177.8** |
DMH + DSS + Ru-B 100 mg/kg | 6 ± 1.1 | 12 ± 2.01 | 14 ± 3.7 | 10 ± 1.7 | 8 ± 0.9 | 50 ± 9.41 ** |
DMH + DSS + Ru-B 200 mg/kg | 10 ± 0.6 | 9 ± 1.6 | 10 ± 2.3 | 7 ± 0.5 | 4 ± 1.9 | 40 ± 6.9 *** |
DMH + DSS + 100 mg/kg Baicalein | 22 ± 1.3 | 31 ± 2.05 | 29 ± 0.6 | 26 ± 3.1 | 19± 2.8 | 127± 9.85 |
DMH + DSS + 100 mg/kg Ruthenium | 24 ± 0.5 | 21 ± 2.9 | 20 ± 1.9 | 17 ± 1.5 | 16± 0.8 | 98 ± 7.6* |
All the data are expressed as mean ± S.E. n = 6. Results were analysed by t test and one-way ANOVA and confirmed by Dunett's multiple comparison tests. * p<0.05, Significant difference between ruthenium 100 mg/kg and DMH and DSS control group, ** p<0.05. Significant difference between Ru-B 50 mg/kg and Ru-B 100 mg/kg and DMH and DSS control group, ***p<0.01, Significant difference between Ru-B 200 mg/kg and DMH and DSS control group.