Table 1.
Sociodemographic characteristics of the study population.
| Variable | Sepsis N = 270 | Infected but non-septic N = 270 | P value |
|---|---|---|---|
| Age (years) | 61 (48-75) | 57 (43-71) | .01 |
| Male | 135 | 141 | .6 |
| Female | 135 | 129 | .6 |
| Creatinine (mg/dL) | 1 (0.75-2.01) | 0.78 (0.64-0.96) | <.001 |
| BUN (mg/dL) | 24.9 (16.3-44.5) | 13.7 (10.42-19) | <.001 |
| Bilirubin total (mg/dL) | 0.4 (0.22-0.8) | 0.2 (0.2-0.4) | <.001 |
| NT-proBNP (pg/mL) | 2099 (590-8937) | 329 (153-867) | <.001 |
| Troponin I (ng/mL) | 0.1 (0.1-0.4) | 0.1 (0.1-0.1) | .2 |
| MAP (mmHg) | 68 (62-79) | 70 (68-75) | <.001 |
| Platelets (mm3) | 232 (168-303) | 248 (194-307) | .020 |
| SOFA | 2 (1-5) | 0 (0-1) | <.001 |
| APACHE | 12.5 (8-18) | 7 (5-10) | <.001 |
| CHARLSON | 1 (1-3) | 1 (0-2) | .1 |
| MMP-9 (ng/mL) | 589 (229-1098) | 196 (120-300) | <.001 |
| TIMP-1 (ng/mL) | 306 (170.5-579.2) | 847 (615.8-1169) | <.001 |
Data presented as median (25th to 75th percentile).
Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; BUN, blood urea nitrogen; CHARLSON, Charlson Comorbidity Index; MAP, mean arterial pressure; MMP-9, matrix metalloproteinase 9; NT-proBNP, cerebral natriuretic peptide; SOFA, Sequential Organ Failure Assessment; TIMP-1, tissue inhibitor of metalloproteinase 1.