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. 2019 May 19;11:1759091419845524. doi: 10.1177/1759091419845524

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Correlation of Aβ₄₂, Aβ_42/40, and Aβ₄₀ between the two centers for APOE ε4 carriers (a to c) and non APOE ε4 carriers (d to f). Cases with CSF concentrations above the detection limit were excluded; 53 APOE ε4 cases (a to c) and 71 (e and f) or 70 (e) non APOE ε4 cases were included. Correlation was significantly lower (p = .036) in APOE ε4 carriers for Aβ₄₂ between the two centers (a and d), whereas similar correlations could be observed for Aβ_42/40 and Aβ₄₀. Concordant CSF biomarkers were defined as consistent CSF levels in both centers above or below the corresponding cutoff values. Areas with concordant cases are colored green, whereas areas with discordant cases are colored orange in Panels (a), (b), (d), and (e). *Comparison of correlation between APOE ε4 carriers and noncarriers for each biomarker after Fisher r-to-z transformation. APOE = apolipoprotein E; Aβ = amyloid-beta; Aβ₄₂ = Aβ 1-42; Aβ_42/40 = Aβ₄₂ to Aβ 1-40 ratio.