Table 2.
Effects of Quinine (Qu) on Spontaneous EPSCs and IPSCs of OT Neurons.
| Groups | Amp (pA) | Duration, FWHM (ms) | Rise time, tau (ms) | Decay time, tau (ms) | Freq. (Hz) |
|---|---|---|---|---|---|
| EPSCs | |||||
| Control (n = 6) | 15.7 ± 1.3 | 3.5 ± 0.3 | 6.5± 1.0 | 34.0 ± 18.9 | 5.4 ± 1.7 |
| Qu-10 min (n = 6) | 16.5 ± 1.7 | 3.1 ± 0.3* | 10.2 ± 3.8 | 19.5 ± 7.5 | 6.0 ± 1.3 |
| Qu-20 min (n = 5) | 14.1 ± 2.1 | 3.3 ± 0.4 | 6.9 ± 2.2 | 21.1 ± 6.7 | 2.7 ± 0.7 |
| IPSCs | |||||
| Control (n = 6) | 28.0 ± 4.3 | 6.8 ± 0.3 | 12.3 ± 6.1 | 29.1 ± 12.41 | 4.3 ± 0.4 |
| Qu-10 min (n = 6) | 25.3 ± 3.8* | 6.5 ± 0.3 | 26.6 ± 21.1 | 28.1 ± 8.41 | 4.2 ± 0.8 |
| Qu-20 min (n = 3) | 20.0 ± 5.8 | 6.1 ± 0.7 | 5.9 ± 0.9 | 39.1 ± 11.07 | 3.6 ± 1.0 |
Note. Rise and decay times are given as time constants (tau) to reach 1-1/e and 1/e of the peak amplitude, respectively. *p < .05 compared with control, one-way ANOVA with Tukey’s post hoc test, as well as χ2 test (see text for details). EPSC = excitatory postsynaptic potential; IPSP = inhibitory postsynaptic potential; OT = oxytocin; Amp = amplitude; FWHM = the full with at half maximum; Freq = frequency of events.