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. 2019 May 23;12:4047–4054. doi: 10.2147/OTT.S200873

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© 2019 Zhou et al.

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Inhibition of YAP activity enhances calotropin-induced anti-proliferative effect. (A and B) Cell viability was measured by MTT assay in cells treated with DMSO or CTP for 24 hrs in the presence and absence of Verteporfin (VP). (C and D) Cell proliferation was measured using BrdU labeling in cells treated with DMSO or CTP for 24 hrs in the presence and absence of VP. (E and F) Cells were transfected with siYAP or control for 48 hrs and then treated with CTP for 24 hrs, and cell viability was measured by MTT assay. *P<0.05, **P<0.01.

Abbreviations: CTP, calotropin; DMSO, dimethyl sulfoxide.