Table 3.
Literature | Year of study | No. of patients | EBRT dose (Gy) | BT dose × fractions | Bladder 2 cm3 (Gy3) | Rectum 2 cm3 (Gy3) | Sigmoid 2 cm3 (Gy3) | D90 CTVHR (Gy10) |
---|---|---|---|---|---|---|---|---|
Pötter et al. [9] | 2011 | 156 | 50.4 | 7 Gy × 4 | 86 | 65 | 64 | 93 |
Jamalludin et al. [10] | 2016 | A | 48.6 | 7 Gy × 4 | 80.8 | 81.7 | 73.9 | – |
B | 45.4 | 7.5 Gy × 3 | 80.4 | 82.8 | 65.9 | – | ||
Kirisits et al. [11] | 2005 | 22 | 45 | 7 Gy × 4 | 83 | 64 | 63 | 87 |
Beriwal et al. [12] | 2011 | 44 | 45 | 5-6 Gy × 4 | 79.7 | 57.5 | 66.8 | 83.3 |
Tharavichitkul et al. [13] | 2013 | 47 | 45 | 6.5-7 Gy × 4 | 88.2 | 69.6 | 72 | 93.1 |
Nomden et al. [14] | 2013 | 46 | 45 | 7 Gy × 4 | 83 | 66 | 61 | 84 |
Wang et al. [15] | 2016 | 42 | 46 | 5 Gy × 5 | 86 | 72.9 | 73.27 | 73.82 |
Present study | 50 | 45 | 5.5 Gy × 5 | 74.06 | 67.43 | 54.56 | 85.9 | |
45 | 6.5 Gy × 4 | 73.75 | 67.57 | 54.43 | 84.67 | |||
45 | 7 Gy × 4 | 77.27 | 71.11 | 55.44 | 89.03 | |||
45 | 9 Gy × 2 | 68.58 | 64.82 | 52.14 | 69.16 |
EBRT – external beam radiotherapy, BT – brachytherapy, D90 – dose received by 90% of the CTVHR