. 2019 May 13;21(5):e11349. doi: 10.2196/11349

Table 2.

Baseline adjusted symptom measures at 3, 6, and 15 months: guided Web-based rumination-focused cognitive behavioral therapy versus usual care controls.

Timepoint and measure		Guided Web-based rumination-focused cognitive behavioral therapy, mean (95% CI)	Usual care, mean (95% CI)	Between-group difference, difference (95% CI)	Estimated between-group difference after multiple imputations, multiple imputation difference (95% CI)
Follow-up 1 (3 months; n=114)
	PHQ-9^a	4.75 (3.74 to 5.76)	5.40 (4.48 to 6.33)	−0.65^b (−2.02 to 0.72)	−0.55^b (−2.05 to 0.96)
	GAD-7^c	5.58 (4.51 to 6.66)	6.27 (5.28 to 7.25)	−0.69^b (−2.15 to 0.78)	−0.53^b (−2.14 to 1.09)
	PSWQ^d	57.27 (54.85 to 59.69)	58.45 (56.23 to 60.67)	−1.18^b (−4.46 to 2.11)	−0.75^b (−4.35 to 2.86)
	RRS^e	44.34 (41.66 to 47.02)	48.21 (45.73 to 50.68)	−3.87^f (−7.53 to −0.21)	−3.69^b (−8.01 to 0.63)
Follow-up 2 (6 months; n=105)
	PHQ-9	3.70 (2.48 to 4.92)	5.52 (4.42 to 6.62)	−1.82^f (−3.46 to −0.18)	−1.97^f (−3.87 to −.063)
	GAD-7	4.72 (3.44 to 5.99)	6.06 (4.91 to 7.20)	−1.34^b (−3.05 to 0.38)	−1.15^b (−3.16 to 0.85)
	PSWQ	54.83 (52.19 to 57.48)	58.41 (56.03 to 60.79)	−3.58^f (−7.14 to −0.02)	−2.71^b (−6.68 to 1.25)
	RRS	41.74 (38.15 to 45.34)	46.35 (43.12 to 49.58)	−4.60^b (−9.47 to 0.26)	−3.98^b (−9.48 to 1.52)
Follow-up 3 (15 months; n=108)
	PHQ-9	4.47 (3.23 to 5.71)	4.82 (3.73 to 5.91)	−0.35^b (−2.00 to 1.30)	−0.38^b (−2.30 to 1.55)
	GAD-7	4.42 (3.16 to 5.68)	5.73 (4.62 to 6.83)	−1.31^b (−2.99 to 0.38)	−1.10^b (−2.10 to 0.80)
	PSWQ	54.81 (51.71 to 57.91)	58.11 (55.39 to 60.84)	−3.30^b (−7.43 to 0.82)	−1.74^b (−6.53 to 3.06)
	RRS	46.15 (42.59 to 49.72)	44.65 (41.53 to 47.78)	1.50^b (−3.28 to 6.28)	1.16^b (−3.99 to 6.31)

^aPHQ-9: Patient Health Questionnaire.

^bNot significant.

^cGAD-7: Generalized Anxiety Disorder Screener.

^dPSWQ: Penn State Worry Questionnaire.

^en=115 for Ruminative Response Scale (RRS) at 3 months owing to one partially completed questionnaire set.

^fP<.05.