Menthol does not impact body weight during extended access self-administration or abstinence. (a) Mean (± SEM) body weights prior to the first extended access session (session 1), and then throughout extended access self-administration (sessions 3,5,8,10) and abstinence (days 2,5,7,9) for the Nic (n=11; black circles), Ment (n=11; white circles), Nic+Mentlow
(n=13; white circles with black stripes), Nic+Mentmod
(n=16; light gray circles) and Nic+Menthigh
(n=16; dark gray circles with grid pattern) groups. A plus (+) sign with dashed lines indicates a significant difference in the body weights prior to the first extended access session versus the last day of abstinence. (b) Mean (± SEM) percent change in body weight from the first extended access session to the last day of abstinence for the Nic (black bar), Ment (white bar), Nic+Mentlow
(white bar with black stripes), Nic+Mentmod
(light gray bar) and Nic+Menthigh
(dark gray bar with grid pattern) groups.