Table 2. Prognostic Factors for Disease Control Status.
| Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|
| Disease-controlled (n=79) | Disease-uncontrolled (n=55) | p value | p value | B | SE | Odds ratio | |
| Age (yr) | 54 (47–61) | 46 (34–58) | 0.003* | 0.015‡ | −0.038 | 0.158 | 0.963 |
| Sex (male:female) | 63:16 | 17:38 | 0.228† | ||||
| Atopic | 37/77 (48.1) | 24/53 (45.3) | 0.895† | ||||
| Asthma | 6/78 (8.3) | 10/55 (18.1) | 0.119† | ||||
| Symptom duration (month) | 36.0 (6.6–120.0) | 60.0 (18.0–120.0) | 0.116* | ||||
| Lund-Mackay score | 14 (11–18) | 19 (13–22) | <0.001* | 0.045‡ | 0.158 | 0.079 | 1.171 |
| Global osteitis score | 10 (5–18) | 20 (9–24) | 0.002* | 0.510‡ | −0.028 | 0.043 | 0.972 |
| BTT | 5 (0–8) | 2 (0–7) | 0.096* | ||||
| Tissue eosinophil (cells/HPF) | 10.0 (2.3–40.7) | 25.5 (4.1–92.0) | 0.025* | 0.032‡ | 0.009 | 0.004 | 1.009 |
| Tissue neutrophil (cells/HPF) | 11.8 (6.0–23.0) | 24.0 (8.9–59.9) | 0.002* | 0.005‡ | 0.023 | 0.008 | 1.023 |
| Blood eosinophil (cells/mm3) | 229 (119–328) | 278 (132–582) | 0.091* | ||||
| Blood neutrophil (cells/mm3) | 3663 (3040–4287) | 3903 (2849–5155) | 0.390* | ||||
| Current smoking | 23/79 (29.1) | 24/77 (32.7) | 0.798† | ||||
| Smoking history (pack-year) | 0 (0–10) | 0 (0–5) | 0.801* | ||||
| Alcohol intake (g/month) | 56 (0–448) | 0 (0–252) | 0.427* | ||||
| Heavy drinker | 12/78 (15.4) | 5/55 (9.1) | 0.420† | ||||
| BMI (kg/m2) | 24.6 (22.6–26.3) | 23.6 (21.6–25.2) | 0.116* | ||||
BTT, butanol threshold test; HPF, high power field; BMI, body mass index; B, standardized coefficient; SE, standard error.
Values are presented as medians with IQRs or numbers (percentages).
*Mann-Whitney U-test, †Pearson chi-square test, ‡Binary logistic regression analysis.