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. 2019 May 22;60(6):578–584. doi: 10.3349/ymj.2019.60.6.578

Table 3. Subgroup Analysis of Non-ECRSwNP and ECRSwNP Groups.

Non-ECRSwNP (n=57) p value ECRSwNP (n=77) p value
Disease-controlled (n=33) Disease-uncontrolled (n=24) Disease-controlled (n=46) Disease-uncontrolled (n=31)
Age (yr) 54 (45–61) 51 (31–59) 0.301* 56 (51–60) 42 (3–54) 0.002*
Sex (male:female) 25:8 17:7 0.911 38:8 21:10 0.093
Atopic 18/33 (54.5) 13/23(43.5) 1.000 22/44 (50) 14/30 (46.7) 0.964
Asthma 1/33 (3.0) 2/24 (8.3) 0.567 5/45 (11.1) 8/31 (25.8) 0.125
Symptom duration (month) 13.4 (3.3–72.0) 67.7 (24.0–120.0) 0.021* 42 (12–150) 60 (18–120) 0.989*
Lund-Mackay score 14 (11–18) 18 (11–20) 0.274* 14 (10–17) 20 (15–22) <0.001*
Global osteitis score 9 (6–18) 16 (2–23) 0.096* 11 (4–17) 20 (10–26) 0.008*
BTT 4 (0–8) 3 (0-8) 0.499* 5 (0–8) 0 (0–5) 0.084*
Tissue eosinophil (cells/HPF) 3.3 (0.5–10.6) 10.4 (1.3–29.9) 0.166* 17.3 (6.7–80.0) 70.0 (15.9–105.0) 0.054*
Tissue neutrophil (cells/HPF) 16.5 (9.0–26.8) 46.0 (21.5–69.5) 0.004* 10.3 (3.0–17.7) 15.0 (6.1–40.6) 0.125*
Blood eosinophil (cells/mm3) 116 (79–150) 115 (60–208) 0.897* 308 (239–417) 437 (346–707) 0.002*
Blood neutrophil (cells/mm3) 3623 (3205–4384) 4027 (3022–5251) 0.678* 3702 (2607–4124) 3892 (2779–4879) 0.508*
Current smoking 10/33 (30.3) 7/24 (29.2) 1.000 13/46 (28.3) 11/31 (35.5) 0.674
Smoking history (pack-year) 0 (0–18.4) 0 (0–2.5) 0.855* 0 (0–6.0) 0 (0–6.3) 0.587*
Alcohol intake (g/month) 100 (0–672) 28 (0–168) 0.211* 0 (0–224) 0 (0–324.8) 0.928*
Heavy drinker 8/33 (3.4) 3/24 (20) 0.326 4/45 (8.9) 2/31 (6.5) 1.000
BMI (kg/m2) 24.6 (22.6–26.0) 23.3 (21.4–26.2) 0.268* 24.6 (22.4–26.3) 23.8 (21.9–24.9) 0.262*

ECRSwNP, eosinophilic chronic rhinosinusitis with nasal polyps; BTT, butanol threshold test; HPF, high power field; BMI, body mass index.

Values are presented as medians with IQRs or numbers (percentages).

*Mann-Whitney U-test, Pearson chi-square test, Fischer's exact test.