Figure 7.

Foxp3 actives miR‐664a‐3p expression. A, The expression of Foxp3 in 58 pairs of GC specimens. B, The expression of Foxp3 in GC cells compared to GES‐1. C, The survival analysis of Foxp3 on the Kaplan‐Meier Plotter. D, Bioinformatic analysis indicated that Foxp3 might bind to miR‐664a‐3p promoter. E, Relative luciferase activity was analyzed in HEK293 cell. F, ChIP assay was performed with control (rat IgG), anti‐Foxp3 antibody to determine Foxp3 occupancy of miR‐664a‐3p promoter. G,H, The relative expression of miR‐664a‐3p altered when transfected Lv‐Foxp3, Pex3, and sh‐Foxp3 in SGC7901 and HGC27. Pex3 was control vector. I,J, qRT‐PCR was used to detected the relative expression of MOB1A when the level of Foxp3 was altered